Madison Medical Affiliates serves the downtown community, as well as southeastern Wisconsin, with a list of Board Certified physicians - many of whom have been recognized by Milwaukee Magazine as Milwaukee's Top Doctors. Our practice has grown to include 23 physicians and 80 professional staff, and has a longstanding affiliation with Columbia St. Mary's. With our convenient and centrally located Cathedral Square clinic, along with locations at Columbia Hospital on the East Side and St. Mary's Hospital in Milwaukee and Mequon, we are always nearby to assist our patients with their healthcare needs. A century of distinguished service to the community. Since 1903, Madison Medical Affiliates has provided quality care to residents of southeastern Wisconsin. Rooted in the tradition of excellence set by founder J.D. Madison, M.D., the clinic was first opened in the Goldsmith Building at 425 East Wisconsin Avenue and the “Goldsmith Gang” remained there until the building was torn down in the 1970s. The practice began to grow and flourish in 1926 when Dr. J.D. Madison teamed with his nephew and pioneer in hematology, Dr. Fred Madison. Now located at 788 North Jefferson Street, Madison Medical Affiliates is entering its second century as Milwaukee's premier internal medicine group. Although the faces have changed, our commitment to healthcare and excellence has always remained the same. Even our telephone number has remained the same - 414.272.8950. As downtown continues to evolve, Madison Medical Affiliates is expanding to serve the growing downtown business and residential community as well as at our other locations on Milwaukee's Northshore and East Side.